4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.
ChEBI: 4-nitro-1,3-phenylenediamine is a C-nitro compound.
Orange prisms with blue luster or yellow crystalline solid.
4-Nitro-1,3-phenylenediamine is an amine/organonitrate. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Flash point data for 4-Nitro-1,3-phenylenediamine are not available, but 4-Nitro-1,3-phenylenediamine is probably combustible.
Moderately toxic by ingestion.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx.
