Chemical Properties
Yellow crystal powder
Uses
4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.
Definition
ChEBI: 4-nitro-1,3-phenylenediamine is a C-nitro compound.
General Description
Orange prisms with blue luster or yellow crystalline solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
4-Nitro-1,3-phenylenediamine is an amine/organonitrate. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for 4-Nitro-1,3-phenylenediamine are not available, but 4-Nitro-1,3-phenylenediamine is probably combustible.
Safety Profile
Moderately toxic by ingestion.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx.
