2,2'-Azodi(2-methylbutyronitrile) is used in biochemical reagents, polymer initiators, surfactants, etc.
To 328 g of sodium cyanide (NaCN) (30%), 14.4 g of butanone was added dropwise, 10 g of hydrazine hydrate (80%) was added dropwise, and 30% sulfuric acid was added dropwise below a controlled temperature of 30C to Ph = 7, and the reaction took 3 hours. The organic phase was obtained by static layering. The above organic phase, add 30% sulfuric acid 40g, potassium bromide 0.6g, drop 30% hydrogen peroxide 11.3g, controlled temperature 45 , reaction for 5 hours, filtration, methanol recrystallization of the product. Yield 85%.
