Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form
Powder
pka
9.00±0.50(Predicted)
Usage And Synthesis
Uses
Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A)-induced cardiotoxicity[1].
target
NF-kB | NOS | ROS
References
[1] Chen C , et al . Isodunnianol alleviates duxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019 May 22;10(5):2651-2657. DOI:10.1039/c9fo00063a
