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beta-Sitosterol

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beta-Sitosterol Basic information
beta-Sitosterol Chemical Properties
  • Melting point:136-140 °C(lit.)
  • alpha -28 º (c=2, CHCl3)
  • Boiling point:473.52°C (rough estimate)
  • Density 0.9540 (rough estimate)
  • refractive index 1.5000 (estimate)
  • storage temp. 2-8°C
  • solubility chloroform: 20 mg/mL, clear, colorless
  • form White solid
  • pka15.03±0.70(Predicted)
  • Water Solubility INSOLUBLE
  • Merck 14,8556
  • BRN 1916165
  • InChIKeyKZJWDPNRJALLNS-VJSFXXLFSA-N
  • CAS DataBase Reference83-46-5(CAS DataBase Reference)
  • NIST Chemistry Reference«beta»-Sitosterol(83-46-5)
  • EPA Substance Registry System.beta.-Sitosterol (83-46-5)
Safety Information
MSDS
beta-Sitosterol Usage And Synthesis
  • Chemical PropertiesWhite powder
  • UsesA common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma.
  • Usesantiinflammatory, immunomodulator
  • DefinitionChEBI: A phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3.
  • DefinitionA steroid with long aliphatic side chains (8–10 carbons) and at least one hydroxyl group. They are lipidsoluble and often occur in membranes. Examples are cholesterol and ergosterol.
  • Definitionsterol: Any of a group of steroidbasedalcohols having a hydrocarbonside-chain of 8–10 carbon atoms.Sterols exist either as free sterols oras esters of fatty acids. Animal sterols(zoosterols) include cholesterol andlanosterol. The major plant sterol(phytosterol) is beta-sitosterol, whilefungal sterols (mycosterols) includeergosterol.
  • Purification MethodsCrystallise -sitosterol from EtOH, MeOH, Me2CO, Me2CO/EtOH or Me2CO/MeOH. It has also been purified by zone melting. The acetate crystallises from MeOH or EtOH as plates with m 127128o and [] D 20 -41o (c 2, CHCl3). The benzoate crystallises from EtOH as needles with m 146-147o and [] D 20 –13.8o (c 2, CHCl3). [Fujimoto & Jacobson J Org Chem 29 3377, 3381 1964, Shoppee J Chem Soc 10431948, Heilbron et al. J Chem Soc 344, 347 1941, Beilstein 6 III 2696.]
beta-Sitosterol Preparation Products And Raw materials
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