2,6-Naphthalenedicarboxylic acid (2,6-NDA) is selectively synthesized from 2-naphthoic acid (2-NCA) and carbon tetrachloride in aqueous sodium hydroxide solution under mild conditions using cyclodextrin (β-CyD) as a catalyst
[1]. The specific reaction steps are as follows:
Three mmol of 2-naphthalenecarboxylic acid/2-NCA), 0,8 mmol(0,05 g) of copper powder, and 3,0 mmol of β-CyD were added to 30 mL of 30 wt.-% aqueous sodium hydroxide solution. The reaction was started with the addition of 8,5 mmol of carbon tetrachloride and was continued at 60°C for 7 h with magnetic stirring under nitrogen. Then, the residual carbon tetrachloride was removed by evaporation under reduced pressure.
