盐酸胡芦巴碱
盐酸胡芦巴碱 性质
| 熔点 | ~260 °C (dec.) |
|---|---|
| 储存条件 | Inert atmosphere,Room Temperature |
| 溶解度 | 少许溶于甲醇、可溶于水 |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| Merck | 14,9694 |
| BRN | 3734169 |
| 稳定性 | 吸湿性 |
| 主要应用 | food and beverages |
| InChI | InChI=1S/C7H7NO2.ClH/c1-8-4-2-3-6(5-8)7(9)10;/h2-5H,1H3;1H |
| InChIKey | TZSYLWAXZMNUJB-UHFFFAOYSA-N |
| SMILES | C1=[N+](C)C=CC=C1C([O-])=O.[H]Cl |
| CAS 数据库 | 6138-41-6(CAS DataBase Reference) |
盐酸胡芦巴碱 用途与合成方法
It is found that Trigonelline chloride (TG) significantly rescues the morphology of the H9c2 cells. Treatment of cells with Trigonelline chloride attenuates H 2 O 2 induced cell deaths and improves the antioxidant activity. In addition, Trigonelline chloride regulates the apoptotic gene caspase-3, caspase-9 and anti-apoptotic gene Bcl-2, Bcl-XL during H 2 O 2 induced oxidative stress in H9c2 cells. For evident, flow cytometer results also confirm that Trigonelline chloride significantly reduces the H 2 O 2 induced necrosis and apoptosis in H9c2 cells. However, further increment of Trigonelline chloride concentration against H 2 O 2 can induce the necrosis and apoptosis along with H 2 O 2 .
Trigonelline chloride decreases bone mineralization and tends to worsen bone mechanical properties in streptozotocin-induced diabetic rats. In nicotinamide/streptozotocin-treated rats, Trigonelline chloride significantly increases bone mineral density (BMD) and tends to improve cancellous bone strength. Trigonelline chloride differentially affects the skeletal system of rats with streptozotocin-induced metabolic disorders, intensifying the osteoporotic changes in streptozotocin-treated rats and favorably affecting bones in the non-hyperglycemic (nicotinamide/streptozotocin-treated) rats.
盐酸胡芦巴碱 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-03-03 | S3802 | 盐酸胡芦巴碱 | 6138-41-6 | 25mg | 795.06 |
| 2025-12-22 | HY-N0415 | 盐酸胡芦巴碱 | 6138-41-6 | 100mg | 500 |
