Basic information Uses Safety Related Supplier
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Nucleoside drugs >  Nucleotides and their analogs >  4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Basic information Uses Safety Related Supplier
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Basic information
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties
  • Melting point:188-194 °C
  • Boiling point:289.2±50.0 °C(Predicted)
  • Density 1.61±0.1 g/cm3(Predicted)
  • storage temp. Keep in dark place,Inert atmosphere,2-8°C
  • solubility Soluble in DMSO, ethyl acetate and methanol.
  • form Crystalline Powder
  • pka11.42±0.20(Predicted)
  • color White to tan
  • InChIKeyBPTCCCTWWAUJRK-UHFFFAOYSA-N
  • CAS DataBase Reference3680-69-1(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xi,T,Xn
  • Risk Statements 36/37/38-25-20/21/22
  • Safety Statements 26-37-45-36
  • RIDADR UN 2811 6.1/PG 3
  • WGK Germany 3
  • RTECS UY9360000
  • TSCA No
  • HazardClass IRRITANT
  • PackingGroup 
  • HS Code 29335990
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Usage And Synthesis
  • Uses

    4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is an important pharmaceutical intermediate, which is widely used in the synthesis of many pharmaceutical intermediates at home and abroad. Including CP690550, CGP76030 and so on, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine was the scaffold for many commercially available drugs. Also, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine was the intermediate of the bulk drug, Tofatinib, which was widely used in treatment of adult patients with moderate to severe rheumatoid arthritis with inadequate or intolerant methotrexate response.

  • Chemical PropertiesLightbrown to brown crystalline powder
  • Uses4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is used in the manufacture of Tofacitinib citrate.
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine(3680-69-1)Related Product Information
4-Chloro-7H-pyrrolo[2,3-d]pyrimidineSupplierMore
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  • Company Name:NanJing FineTech Chemical Co., Ltd Gold
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