Gabapentin-Related Compound B (also known as 1-cyanocyclohexaneacetic acid) is a reference standard for gabapentin-related drug impurities. It is primarily used for pharmaceutical quality control, impurity profiling, and the identification and quantification of related substances in gabapentin active pharmaceutical ingredients (APIs) and finished dosage forms.
Gabapentin Related Compound B (Gabapentin EP Impurity B; Gabapentin USP Related Compound B) is a Gabapentin analogue for treatment of neurological disorders.
A process for preparing 1-cyanocyclohexaneacetic acid from 1-cyanocyclohexaneacetonitrile comprising the steps of (a) contacting 1-cyanocyclohexaneacetonitriIe with an enzyme catalyst having nitrilase activity in an aqueous reaction mixture; and (b) recovering 1-cyanocyclohexaneacetic acid from the aqueous reaction mixture.
