Semax is a synthetic analogue of the adrenocorticotropic hormone, a hormone responsible for the
production of cortisol which in turn regulates glucose and lipid metabolism and helps to maintain
blood pressure. In the hippocampus, Semax rapidly elevates the levels of brain-derived neurotrophic
factor (BDNF), a protein important in encouraging growth and differentiation of new neurons and
synapses. BDNF is active in the hippocampus, cortex, and forebrain and is important for memory,
coordination, concentration, and learning. Semax also works to activate the dopaminergic and
serotonergic systems to help prime the brain for action and to induce a controlled state of mental
stress.
Over continued use, guests have seen benefits such as:Reduces anxiety and depression;Improves mental clarity, memory, and focus
Semax altered the expression of genes that modulate the amount and mobility of immune cells. It also could enhanced the expression of genes that encode chemokines and immunoglobulins. It can increase attention and short-term memory, improve Non-proliferative Diabetic Neuropathy, and can help during recovery from Stroke/Hypoxia
Though the exact mechanism of action of Semax is unclear, there is evidence that it may act through melanocortin receptors. Semax is a neuroprotective peptide, which aims to slow disease progression and secondary injuries by halting/slowing the loss of neurons and is neurorestorative.
Semax has been prescribed for anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal and even chronic diseases such as ALS, Parkinson’s Disease, and Alzheimer’s. Semax has been known to be used as an Adderall alternative.
Semax has undergone extensive study in Russia and is on the Russian List of Vital & Essential Drugs approved by the Russian Federation government on December 7, 2011. Medical uses for Semax include treatment of stroke, transient ischemic attack, memory and cognitive disorders, peptic ulcers, optic nerve disease, and to boost the immune system.
While Semax is widely recognized for its cognitive benefits, like many nootropics, it also has potential side effects. Some individuals have reported instances of headaches, weariness, irritability, and mild stomach pain. It is noteworthy to acknowledge that these adverse effects are infrequent and typically resolve expeditiously. However, anyone considering Semax should consult with a healthcare provider before starting a regimen to gauge personal risk and ensure safe use.
