Nuclease S7 has been used in ribonuclease selection process for ribosome profiling.
Micrococcal Nuclease can be used for the digestion of chromatin to identify the location of nucleosomes.
Nuclease from Staphylococcus aureus has been used in a study to assess coagulase and heat-resistant strains found in animals. It has also been used in a study to investigate the expression characteristic of two genes in S. aureus that encode two thermostable nucleases.
Cleavage of DNA by Nuclease micrococcal is greater at the 5′ sides of A or T nucleotides than at G or C.