2-Chloro-4-nitrophenol

white to beige crystalline powder or crystals

2-Chloro-4-nitrophenol, is frequently used as building blocks for dyes, plastics, explosives. It acts as a catalytic agent, petrochemical additive and used in organic synthesis. It can react with sulfuric acid dimethyl ester to produce 2-chloro-4-nitro-anisole. This reaction will need reagents K2CO3 and xylene.

Not classified

In the 500 ml four-necked bottle equipped with a thermometer, stirrer, reflux condenser and tail gas absorption device plus add 60 grams of 99% p-nitrophenol (0.427 mole) and 240 grams of solvent dichloroethane, stirring and heated to 55-65 , the opening of the vacuum tail gas absorption system to ensure that the micro-negative -0.01-0.02MPa conditions, and then pass into the chlorine, the use of GC tracking Reaction process, until the raw material reaction is completed. First of all, atmospheric pressure desolvation and recovery of solvent dichloroethane direct set of use, and then decompression at 10mmHg distillation residual solvent dichloroethane recovery set of steam, to obtain the crude o-chloro-p-nitrophenol, cooled down to 50 C to the following plus 200 grams of toluene, warmed up to the full solubility of the natural precipitation of the temperature is slowly lowered, and then the ice bath cooling to (0-5) C stirring for an hour and then add filtration, drying to get 71.5 grams of 2-chloro-4-nitrophenol, 95.1% yield, GC tracking. Yield 95.1%, GC qualitative content of 99%.