Sulbenicillin sodium Chemical Properties
- storage temp. Inert atmosphere,Room Temperature
- CAS DataBase Reference28002-18-8(CAS DataBase Reference)
Sulbenicillin sodium Usage And Synthesis
- Manufacturing ProcessTo a suspension of 1.08 parts by weight of 6-aminopenicillanic acid in 8 parts by volume of water is added 1.48 parts by weight of sodium bicarbonate. After the mixture is dissolved, a solution of 1.18 parts by weight of α-sulfophenylacetyl chloride in 10 parts by volume of diethylether is gradually added thereto. The mixture is stirred at a temperature in the neighborhood of 0°C for 1 hour. The aqueous layer is washed twice with 10 parts by volume of portions of ether and adjusted to pH 1.2 with cation exchange resin of polystyrene sulfonic acid type under constant cooling. Then the solution is washed twice with 15 parts by volume of portions of ethyl acetate, followed by extraction twice with 15 parts by volume of portions of n-butanol. The extracts are combined and washed twice with 15 parts by volume of portions of water and, then, extracted with an aqueous solution of sodium bicarbonate. The extract is adjusted to pH 6.5, washed with ether and lyophilized to give the sodium salt of α-sulfobenzylpenicillin. Yield is 1.2 parts by weight.
- Therapeutic FunctionAntibacterial
- Bensulfuron methyl Dimethyl fumarate Dimethyl sulfide Carbenicillin disodium N,N-Dimethylacetamide Sodium formate Sodium chloride Sulbenicillin D(-)- A -SULFOPHENYLACETYL ACID (D-SPA, FOR SULBENICILLIN SODIUM ) DL-SULFOPHENYL ACETIC ACID (DL-SPA, FOR SULBENICILLIN SODIUM ) Furbenicillin sodium Dimethicone Chlorodimethylphenylsilane sodium SULBENICILLIN Furbenicillin CARBENICILLIN Sodium Monofluorophosphate
- Company Name:Chongqing Fuan Pharmaceutical Co., Ltd Gold
- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
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