ChemicalBook Product Catalog Chemical Reagents Organic reagents Halogenated aliphatic hydrocarbons 2-Iodopropane

2-Iodopropane

Product Name2-Iodopropane
CAS75-30-9
MFC3H7I
MW169.99
EINECS200-859-3
MOL File75-30-9.mol

Chemical Properties

Melting point	-90 °C
Boiling point	90 °C
Density	1.703 g/mL at 25 °C(lit.)
refractive index	n20/D 1.498(lit.)
Flash point	108 °F
storage temp.	Store below +30°C.
solubility	1.4g/l
form	Liquid
color	Clear colorless to light yellow
Water Solubility	Soluble in water(1.4g/L).
Thermal Conductivity	0.082 W/(m·K) at 25 ℃
Sensitive	Light Sensitive
Merck	14,5214
BRN	1098244
Henry's Law Constant	8.5×10^-4 mol/(m³Pa) at 25℃, Brockbank (2013)
Dielectric constant	8.1899999999999995
Exposure limits	ACGIH: TWA 0.2 mg/m3; TWA 1 mg/m3 OSHA: TWA 0.1 mg/m3; TWA 1 mg/m3 NIOSH: IDLH 100 mg/m3; TWA 1 mg/m3; TWA 0.1 mg/m3
Stability	Stable, but may discolour on exposure to light. Air sensitive. Incompatible with strong bases, strong oxidizing agents.
InChI	1S/C3H7I/c1-3(2)4/h3H,1-2H3
InChIKey	FMKOJHQHASLBPH-UHFFFAOYSA-N
SMILES	CC(C)I
LogP	2.890
CAS DataBase Reference	75-30-9(CAS DataBase Reference)
NIST Chemistry Reference	Propane, 2-iodo-(75-30-9)
EPA Substance Registry System	Propane, 2-iodo- (75-30-9)

Safety Information

Hazard Codes	Xn
Risk Statements	10-22-36/37/38
Safety Statements	36/37-37/39-26-16
RIDADR	UN 2392 3/PG 3
WGK Germany	3
RTECS	TZ4200000
F	8
TSCA	TSCA listed
HazardClass	3
PackingGroup	III
HS Code	29033990
Storage Class	3 - Flammable liquids
Hazard Classifications	Acute Tox. 4 Oral Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2

MSDS

Provider	Language
Isopropyl iodide	English
SigmaAldrich	English
ACROS	English
ALFA	English

Usage And Synthesis

Chemical Properties

Colorless liquid that discolors in air and light; miscible with chloroform, ether, alcohol and benzene; slightly soluble in water.

Uses

2-Iodopropane is used to prepare butyric and isobutyric acid, as a solvent, also used in medicine and organic synthesis.

Uses

Organic synthesis, pharmaceuticals. 2-Iodopropane (Isopropyl iodide) was used to prepare butyric and isobutyric acid.

Synthesis

2-Iodopropane is produced by reacting hydroxypropyl cellulose (HPC) with hydroiodic acid at 115 °C in a sealed environment[1].

Purification Methods

Treat the iodide with bromine, followed by extraction of free halogen with aqueous Na2S2O3 or NaHSO3, washing with water, drying (MgSO4 or CaCl2) and distilling. (The treatment with bromine is optional.) Other purification methods include passage through activated alumina, or shaking with copper powder or mercury to remove iodine, drying with P2O5 and distilling. Washing with conc H2SO4 or conc HCl (to remove any alcohol), water, aqueous Na2SO3, water and aqueous Na2CO3 has also been used. Treatment with silica gel causes some liberation of iodine. Distillations should be carried out at slightly reduced pressure. Purified isopropyl iodide is stored in the dark in the presence of a little mercury. [Beilstein 1 IV 223.]

References

[1]Chen, X., Hao, D., Wu, Y., Ai, T., & Zhang, Y. (2024). Determination of the degree of molar substitution of hydroxypropyl cellulose by gas chromatography. Journal of Physics: Conference Series, 2783(1), 012068. https://doi.org/10.1088/1742-6596/2783/1/012068

2-Iodopropane

Chemical Properties

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MSDS

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