3-Amino-2-methylbenzyl alcohol

3-Amino-2-methylbenzyl alcohol may be used in chemical synthesis.

To a stirred solution of (2-methyl-3-nitro-phenyl)-methanol (13) (100 mg, 0.598 mmol) in EtOH (5 mL) and water (1 mL) was added powdered iron (183 mg, 3.29 mmol) and ammonium chloride (22 mg, 0.419 mmol), and the resultant mixture was refluxed for 2 hours. The reaction mixture was then brought to room temperature and filtered through a bed of diatomite. The filtrate was diluted with EtOAc, washed with water, dried over sodium sulfate and concentrated under reduced pressure to give 3-amino-2-methylbenzenemethanol (70 mg, 85%) as a yellow gel.