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AG 1478 HYDROCHLORIDE

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AG 1478 HYDROCHLORIDE Basic information
AG 1478 HYDROCHLORIDE Chemical Properties
  • Melting point:247 °C(dec.)
  • Boiling point:458.5±45.0 °C(Predicted)
  • Density 1.337
  • storage temp. Keep in dark place,Inert atmosphere,2-8°C
  • form White to light yellow solid.
  • pka5.54±0.30(Predicted)
  • λmax332nm(lit.)
Safety Information
  • RTECS VA0953000
  • HS Code 29339900
AG 1478 HYDROCHLORIDE Usage And Synthesis
  • UsesA highly potent and specific EGFR tyrosine kinase inhibitor with an IC50 of 3 nM.
  • Biological ActivityPotent and selective inhibitor of epidermal growth factor receptor kinase (IC 50 values 3 nM for EGFR and > 100 μ M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC 50 = 1 μ M).
AG 1478 HYDROCHLORIDE(153436-53-4)Related Product Information
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