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AG 1478 HYDROCHLORIDE

AG 1478 HYDROCHLORIDE Structure
AG 1478 HYDROCHLORIDE
  • CAS No.153436-53-4
  • Chemical Name:AG 1478 HYDROCHLORIDE
  • CBNumber:CB4728982
  • Molecular Formula:C16H14ClN3O2
  • Formula Weight:315.75
  • MOL File:153436-53-4.mol
AG 1478 HYDROCHLORIDE Property
  • Melting point: :247 °C(dec.)
  • Boiling point: :458.5±45.0 °C(Predicted)
  • Density  :1.337
  • storage temp.  :Keep in dark place,Inert atmosphere,2-8°C
  • form  :White to light yellow solid.
  • pka :5.54±0.30(Predicted)
  • λmax :332nm(lit.)
Safety
  • RTECS  :VA0953000
  • HS Code  :29339900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
AG 1478 HYDROCHLORIDE Price More Price(5)
  • Brand: TCI Chemical
  • Product number: T2944
  • Product name : Tyrphostin AG 1478
  • Purity: >98.0%(HPLC)
  • Packaging: 25mg
  • Price: $476
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 10010244
  • Product name : AG-1478
  • Purity: ≥98%
  • Packaging: 1mg
  • Price: $17
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 10010244
  • Product name : AG-1478
  • Purity: ≥98%
  • Packaging: 5mg
  • Price: $77
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 10010244
  • Product name : AG-1478
  • Purity: ≥98%
  • Packaging: 10mg
  • Price: $136
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 10010244
  • Product name : AG-1478
  • Purity: ≥98%
  • Packaging: 25mg
  • Price: $298
  • Updated: 2021/03/22
  • Buy: Buy

AG 1478 HYDROCHLORIDE Chemical Properties,Usage,Production

  • Uses A highly potent and specific EGFR tyrosine kinase inhibitor with an IC50 of 3 nM.
  • Biological Activity Potent and selective inhibitor of epidermal growth factor receptor kinase (IC 50 values 3 nM for EGFR and > 100 μ M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC 50 = 1 μ M).
AG 1478 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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153436-53-4, AG 1478 HYDROCHLORIDERelated Search:
  • N-(3-CHLOROPHENYL)-6,7-DIMETHOXY-4-QUINAZOLINANINE HYDROCHLORIDE
  • 4-(3-CHLOROANILINO)-6,7-DIMETHOXYQUINAZOLINE HCL
  • 4-(3-CHLOROANILINO)-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE
  • AG-1478
  • AG 1478 HYDROCHLORIDE
  • Tyrphostin AG 1478, free base >99%
  • NSC 693255
  • (3-Chlorophenyl)(6,7-dimethoxyquinazolin-4-yl)amine
  • AG1478HCl
  • AG-1478 (Tyrphostin AG-1478)
  • AG-1478 (NSC-693255)
  • AG-1478, 97.5%, a selective EGFR inhibitor
  • AG1478; TYRPHOSTIN AG1478; AG 1478; NSC 693255
  • AG1478; TYRPHOSTIN AG1478; AG 1478
  • AG-1478, >98%
  • -1478 (Tyrphostin Ag
  • -1478)
  • AG 1478 HYDROCHLORIDE USP/EP/BP
  • 153436-53-4
  • C16H14ClN3O2HCl
  • Inhibitors
  • API
  • Inhibitor