white to yellowish crystalline powder
2,5-Dihydroxy-1,4-dithiane has a sulfurous, meaty, toasted bread-like odor
1,4-Dithiane-2,5-diol is a hydroxylated dithiane derivative with phytogrowth-inhibitory and antibacterial activities.
1,4-Dithiane-2,5-diol was used in the synthesis of:
- substituted tetrahydrothiophene derivatives
- 2-amino-3-(arylsulfonyl)thiophenes, potential antiviral and antitumor agents
ChEBI: 1,4-Dithiane-2,5-diol is a member of dithianes.
Aroma characteristics at 0.1% EtoH: sulfurous, grilled meaty, pungent, brothy, eggy, heavy and rich,
toasted bread, tomato
Taste characteristics at 0.25 to 10 ppm: metallic, meaty savory chicken and beef, sulfurous,
egg-yolk-like
1,4-Dithiane-2,5-diol undergoes bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction with chalcones to afford trisubstituted tetrahydrothiophenes. It participates in diastereoselective [3+3] cycloaddition with azomethine imines catalyzed by 1,4-diazabicyclo[2.2.2]octane. It is a mercaptoacetaldehyde dimer and an efficient synthon for incorporating a thiol group to in situ generated nitroalkenes.
