原花青素B1
原花青素B1 性质
熔点 | 231~232℃ |
---|---|
沸点 | 955.3±65.0 °C(Predicted) |
密度 | 1.705±0.06 g/cm3(Predicted) |
储存条件 | Inert atmosphere,2-8°C |
溶解度 | 丙酮(微溶)、乙醇(微溶)、甲醇(微溶)、水(微溶) |
酸度系数(pKa) | 9.29±0.60(Predicted) |
形态 | 固体 |
颜色 | 浅棕色 |
InChIKey | XFZJEEAOWLFHDH-UKWJTHFESA-N |
LogP | 0.300 (est) |
原花青素B1 用途与合成方法
Procyanidin B1 is a polyphenolic flavonoid isolated from fruits and fruit juices, binds to TLR4/MD-2 complex, and has anti-inflammatory activity. Procyanidin B1 causes cellular toxicity at concentrations >100 μg/mL. Procyanidin B1 (100 μg/mL) inhibits LPS-induced TNF-α production, and expression of MD-2, TRAF6, NF-κB mRNA, phosphorylated p38 MAPK and NF-κB protein in THP1 cells. Procyanidin B1 (50-100 µM) protects against Aβ oligomer-induced neuronal death. Procyanidin B1 potently inhibits the activation of caspase-3 at 100 µM, caspase-8 at concentrations of 30, 50, and 100 µM and caspase-9 at concentrations of 10, 30, 50, and 100 µM. Procyanidin B1 (10, 20, 30 μM) significantly and dose-dependently induces expression of ACO and CPT1, with no obvious effect on mRNA expression of PPARα.
药理药效:抗氧活性、抑制肿瘤作用。
原花青素B1是一种B型原花青素,存在于锡兰肉桂中,具有抗炎,抗氧化,抗肿瘤,保护心血管的作用。
原花青素B1 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024-11-11 | XW203152571 | 原花青素B1 | 20315-25-7 | 5MG | 879 |
2024-11-08 | HY-N0795 | 原花青素B1 | 20315-25-7 | 1mg | 600 |