2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇
2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇
![2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 结构式](https://img.chemicalbook.com/CAS/20180527/GIF/20347-71-1.gif)
2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 性质
沸点 | 986.4±65.0 °C(Predicted) |
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密度 | 1.87±0.1 g/cm3(Predicted) |
储存条件 | under inert gas (nitrogen or Argon) at 2-8°C |
溶解度 | DMF:3mg/mL; DMSO:10mg/mL;乙醇:0.5mg/mL; PBS(pH 7.2):10 mg/mL |
形态 | 固体 |
酸度系数(pKa) | 9.24±0.70(Predicted) |
颜色 | 浅棕色至黑色 |
2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 用途与合成方法
Proanthocyanidins are present in plants as complex mixtures of polymers. Predominant food sources are red wine, tea, chocolate and fruits like grapes, apples, pears, and cranberries.
The most interesting antibacterial activity of Proanthocyanidins is related to their presence in cranberries (
Vaccinium macrocarpon
Ait.). A number of clinical trials have demonstrated the effectiveness of cranberry consumption in preventing urinary tract infections (UTIs). Although UTIs can be caused by many microorganisms, more than 85% are caused by Escherichia coli. The presence of P-fimbriae on
E. coli
, which are proteinaceous fibers on the bacterial cell wall, has been clearly established as a virulence factor, since they are responsible by producing adhesions for adherence to uroepithelial cells. Recently, it is demonstrated that cranberry Proanthocyanidins might inhibit P-fimbriated
E. coli
from adhering to uroepithelial cells. The antiadhesion activity of cranberry juice appears to be related to the presence of Proanthocyanidins with at least one A-type linkage.
The effects of cacao liquor Proanthocyanidins on 2- amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced mutagenesis in vivo carcinogenesis in female Sprague-Dawley rats are investigated. In the Ames assay, Proanthocyanidins shows strong antimutagenic effects when assayed in the presence of S-9 mixture. They also inhibit significantly rat pancreatic carcinogenesis in the initiation stage, but not mammary carcinogenesis.
2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024-04-30 | S5105 | 2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 | 20347-71-1 | 25mg | 795.42 |
2024-04-30 | S5105 | 20347-71-1 | 1g | 7944.3 |