This base was first prepared synthetically by Partheil and subsequently discovered
in the roots of Caulophyllurn thalictroides L. It is widespread among the Papilionaceae, being found in Baptisia australis, Genista tinctoria, Sophora
microphylla, S. tetraptera, Thermopsis lanceolata and T. rhombifolia (Watt.)
Richards. It is laevorotatory with [α]20D - 221 ° (H20) and furnishes the following
crystalline salts and derivatives: hydrochloride, m.p. 2S0-SoC (dec.); hydriodide,
m.p. 246-7°C (dec.); perchlorate, m.p. 2S4°C (dec.); aurichloride, m.p.
206°C (dec.); picrate, m.p. 230°C; picrolonate, m.p. 224-SoC (dec.) and the
methiodide which occurs in two modifications, m.p. 248°C and 267-276°C.
N-Methylcytisine (cas# 486-86-2) is a compound useful in organic synthesis.
N-Methylcytisine is a nicotinic alkaloid found in Caulophyllum thalictroides, also known as blue cohosh.
Extremely toxic; cardiotoxic; poisonous.
N-Methylcytisine is toxic and binds selectively to nicotinic acetylcholine receptors in the CNS.
Partheil., Arch. Pharm., 230,448 (1892)
Power, Salway., J. Chem. Soc., 103, 194 (1913)
