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(-)-SPARTEINE

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(-)-SPARTEINE Basic information
(-)-SPARTEINE Chemical Properties
  • Melting point:30.5°C
  • alpha D21 -16.4° (c = 10 in abs alc)
  • Boiling point:137-138 °C1 mm Hg(lit.)
  • Density 1.02 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.528(lit.)
  • Flash point:>230 °F
  • storage temp. 2-8°C
  • pka2.24, 9.46(at 20℃)
  • form liquid
  • optical activity[α]/D -17.5±1.5°, c = 1 in ethanol
  • Water Solubility 3.04g/L(25 ºC)
  • Merck 14,8737
  • BRN 82447
Safety Information
  • Hazard Codes Xn
  • Risk Statements 20/21/22
  • Safety Statements 36
  • RIDADR 3140
  • WGK Germany 3
  • RTECS WG5950000
  • HazardClass 6.1(b)
  • PackingGroup III
MSDS
(-)-SPARTEINE Usage And Synthesis
  • Chemical PropertiesViscous oily liquid; boils around 180°C(356°F); density 1.02 at 20°C (68°F); stronglybasic, a 0.01 M soln. has pH 11.6; slightlysoluble in water (0.3 g/100 mL), dissolvesreadily in alcohol, ether, or chloroform.
  • UsesSparteine occurs in yellow and black lupinbeans (Lupinus luteus L. and L. niger). Italso occurs in other Lupinus species aswell as in Cytisus and Spartium species.Therapeutically, it is used as an oxytocicagent.
  • Health HazardToxic actions of sparteine are similar to thoseof coniine but are much less toxic than thoseof coniine. The toxic symptoms in mice weretremor, muscle contraction, and respiratorydistress. An intraperitoneal dose lethal toguinea pigs is 23 mg/kg.
    LD50 value, oral (mice): 220 mg/kg.
(-)-SPARTEINE(90-39-1)Related Product Information
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