Potassium hydroxide (0.167 g, 2.98 mmol) was added to a suspension of [Ir(cod)Cl]₂ (1.49 mmol) in degassed methanol (100 mL). The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was poured into degassed H₂O (200 mL). The pale yellow solid was filtered off. The pale yellow solid DI-MU-METHOXOBIS(1,5-CYCLOOCTADIENE)DIIRIDIUM(I) was washed with degassed H₂O (50 mL). The pale yellow solid was dried in a vacuum desiccator with P₂O₅ for 2 days. The synthetic route is shown in Figure 1.
Figure: Synthetic route of DI-MU-METHOXOBIS(1,5-CYCLOOCTADIENE)DIIRIDIUM(I)
DI-MU-METHOXOBIS(1,5-CYCLOOCTADIENE)DIIRIDIUM(I), also known as methoxy(cyclooctadiene)iridium(I) dimer, is used as a catalyst in the preparation of heteroaryl fused indole ring systems as inhibition of HCV NS5B polymerase and borylation and Suzuki-miyaura coupling. Further, it is used in tetraborylation reactions, ortho-silylation of aryl ketone, benzaldehyde and benzyl alcohol derivatives through C-H activation. The most useful application is highly regio and enantio selection asymmetric hydroboration. It is a powerful C-H activation catalyst to prepare phenols from arenes. It is also the catalyst of ortho-silylation of aryl ketone, benzaldehyde, and benzyl alcohol derivatives via C-H activation.
Methoxy(cyclooctadiene)iridium(I) dimer is used as a catalyst in the preparation of heteroaryl fused indole ring systems and borylation and Suzuki-miyaura coupling. Further, it is used in tetraborylation reactions, ortho-silylation of aryl ketone, benzaldehyde and benzyl alcohol derivatives through C-H activation. The most useful application is highly regio and enantio selection asymmetric hydroboration.
