clear yellow to orange to brown liquid
Malonyl chloride can be used as a reactant for the synthesis of:
- Alkaloids with tetracyclic cores such as cyclopiamide A and speradine E.
- 6-tetrathiafulvalene(TTF)-polymer by condensation polymerization with TTF-based dihydroxy monomer.
- N-doped TiO2 films by molecular layer deposition.
- Alkyne-substituted 1,3-oxazines by reaction with arylpropynamides.
It can also be used as a coupling agent in the synthesis of block copolymers by anionic polymerization.
Malonyl Dichloride is primarily used an intermediate in the manufacture of pharmaceutical and agrochemical products.
Malonyl chloride can be prepared from Malonic Acid and Thionyl Chloride.
reacts violently with H2O and protic solvents
Malonyl chloride is unstable at rt and should be used freshly distilled in vacuo or freshly prepared; however, it can be stored in the cold for several days; lachrymatory; use in a fume hood.
