1,2-Dihydroxy-3-nitroanthraquinone (cas# 568-93-4) is useful for the development of allosteric PGAM1 inhibitors that are effective at suppressing the proliferation of pancreatic ductal adenocarcinoma cells.
Dyes cloth mordanted with Al orange, with Fe red to violet. As indicator in satd alcohol solution. pH 2.0-4.0, color change from golden orange to flat yellow (in water). pH 5.0-6.5 from yellow to purplish red.
(a) in the presence of boric acid 1,2-Dihydroxyanthracene-9,10-dione?in sulfuric acid in the nitration; (b) 1,2-Dihydroxyanthracene-9,10-dione?in glacial acetic acid, toluene, petroleum ether or the nitration of nitrobenzene.
Crystallise the dye from AcOH (m 244-245o). It has max at 494nm (H2SO4) and forms Cu salts. [Beilstein 8 H 447, 8 II 491, 8 III 3774, 8 IV 2359.]
Properties and Applications
red light brown (chromium), red orange (aluminum). Insoluble in water. In concentrated sulfuric acid to orange, dilution after yellow.
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Standard
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Ironing Fastness
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Light Fastness
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Fulling
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Persperation Fastness
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Soaping
|
Water
|
|
Alkali
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Acid
|
|
ISO
|
3-4
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6
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3-4
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4
|
4
|
4
|
3-4
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