青霉素 V 钾
青霉素 V 钾 性质
| 熔点 | 197-202°C |
|---|---|
| 比旋光度 | D25 +223° (c = 0.2) |
| 密度 | 1.40 |
| 储存条件 | Inert atmosphere,2-8°C |
| 溶解度 | 易溶于水，几乎不溶于乙醇（96%）。 |
| 形态 | 固体 |
| 颜色 | 溶于水 |
| 水溶解性 | Soluble in water, dimethyl sulfoxide, and methanol. |
| BRN | 3899451 |
| BCS Class | 1 (CLogP), 3 (LogP) |
| 稳定性 | 吸湿性 |
| InChIKey | HCTVWSOKIJULET-LQDWTQKMSA-M |
| CAS 数据库 | 132-98-9(CAS DataBase Reference) |
| EPA化学物质信息 | Penicillin V Potassium (132-98-9) |
青霉素 V 钾 用途与合成方法
Penicillin V (0.002-8.0 mg/L) inhibits the growth of
Streptococci
, with the minimum inhibitory concentrations (MICs) of 0.004-0.008 mg/L.
Penicillin V (0.002-8.0 mg/L) inhibits the growth of
C. difficile
, with a MIC
90
of 8 mg/L.
Penicillin V (0.004-0.063 mg/L; 18 h) inhibits the growth of
Staphylococcus aureus
, with a MIC of 0.016 mg/L.
Penicillin V (0.063-0.25 mg/kg; a single s.c.) inhibits the outgrowth of
S. aureus
in mice thigh muscle.
Penicillin V (100 mg/kg; p.o. once daily for 5 d) avoids the fulminant infection of acute purulent otitis media (AOM) in rats.
Penicillin V (2 mg/kg; a single s.c.) exhibits the plasma half-life (61 min) and mean AUC (0.47 mg/L•h).
| Animal Model: | Specific pathogen free (SPF) male Swiss mice (20-25 g) are inoculated S. aureus |
| Dosage: | 0.063, 0.13, 0.25 mg/kg |
| Administration: | A single s.c. |
| Result: | Decreased the number of CFU (1.34×10 7 counts/mL) compared to controls (3.5×10 7 counts/mL) at the dose of 0.25 mg/kg. |
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 22-42/43 |
| 安全说明 | 22-26-36/37-45 |
| WGK Germany | 3 |
| RTECS号 | XH9275000 |
| TSCA | Yes |
| 海关编码 | 29411099 |
| 毒害物质数据 | 132-98-9(Hazardous Substances Data) |
| 毒性 | LD50 orally in rats: >1040 mg/kg (Goldenthal) |
青霉素 V 钾 化学药品说明书
青霉素 V 钾 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-11 | XW13298901 | 青霉素V钾盐 | 132-98-9 | 100G | 2671 |
| 2024-11-08 | 45523 | 青霉素V钾 | 132-98-9 | 5g | 567 |
