ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Quinoline compounds > 4-CHLOROQUINOLINE
4-CHLOROQUINOLINE
- Product Name:4-CHLOROQUINOLINE
- CAS:611-35-8
- MF:C9H6ClN
- MW:163.6
- EINECS:210-267-7
- Mol File:611-35-8.mol
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4-CHLOROQUINOLINE Chemical Properties
- Melting point:28-31 °C(lit.)
- Boiling point:260-261 °C(lit.)
- Density 1.25 g/mL at 20 °C(lit.)
- refractive index 1.6110 (estimate)
- Flash point:>230 °F
- pka3.57±0.13(Predicted)
- Water Solubility Partly soluble in water.
- λmax316nm(EtOH aq.)(lit.)
- BRN 114721
- InChIKeyKNDOFJFSHZCKGT-UHFFFAOYSA-N
- CAS DataBase Reference611-35-8(CAS DataBase Reference)
- NIST Chemistry Reference4-Chloroquinoline(611-35-8)
- Hazard Codes Xi
- Risk Statements 36/37/38
- Safety Statements 26-37/39-36
- WGK Germany 3
- Hazard Note Irritant
- HS Code 29339900
- Language:EnglishProvider:SigmaAldrich
4-CHLOROQUINOLINE Usage And Synthesis
- Chemical PropertiesPale yellow low melting solid
- Purification MethodsPossible impurities include the 2-isomer. It is best purified by converting to the picrate (m 212-213o dec) in EtOH and recrystallising it from EtOH (where the picrate of the 2-chloroquinoline remains in solution) or EtOAc . The picrate is decomposed with 5% aqueous NaOH, extracted in CHCl3, washed with H2O, dried (MgSO4), evaporated and distilled in a vacuum. It can be steam distilled from slightly alkaline aqueous solutions, the aqueous distillate is extracted with Et2O, evaporated and distilled. The distillate solidifies on cooling. [Bobránski Chem Ber 71 578 1938, Beilstein 20/7 V 314.]
4-CHLOROQUINOLINE Preparation Products And Raw materials
- 4-CHLORO-2-METHYLQUINOLINE 2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE 4-Chloro-7-(trifluoromethyl)quinoline 4-CHLORO-6-METHOXY-2-PHENYLQUINOLINE 4-CHLORO-2-METHYL-6-NITROQUINOLINE 1-AZA-2-N-BUTOXY-6,9-DICHLORO-ACRIDINE 9-CHLORO-1,2,3,4-TETRAHYDROACRIDINE 4,8-DICHLOROQUINOLINE 4-CHLORO-6-METHOXYQUINOLINE 6,9-Dichloro-2-methoxyacridine 4-CHLOROQUINALDINE HCL 4-CHLORO-8-ETHYLQUINOLINE 2,4-DICHLOROQUINOLINE 4-CHLORO-6-METHOXY-2-METHYLQUINOLINE 4-Chloro-8-methoxyquinoline 9-Chloroacridine 4-CHLORO-5,8-DIFLUOROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 4-CHLORO-6,8-DIMETHYLQUINOLINE
4-CHLOROQUINOLINESupplierMore
- Company Name:Changzhou Anchor Biological Technology Co., Ltd Gold
- Tel:18915088878
- Email:sales@ankerbio.com;
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- Tel:400-666-7788 010-82848833-
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- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
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- Email:sh@meryer.com