(R)-DIFLUORPHOS(TM)

1. Ligand used for the enantioselective hydrogenation of olefins, and especially electron-poor ketones.
2. Ligand used for the enantioselective α-arylation of ketones.
3. Ligand used for enantioselective alkylative aldol reactions.
4. Nickel-catalyzed asymmetric α-heteroarylation of ketones with chloroarenes.
5. Palladium-catalyzed asymmetric intramolecular arylation of α-keto amides.

(S)-DIFLUORPHOS is an electron-poor diphosphane, and can also be used as a chiral supporting ligand.Also, used in preparation of chiral Amino Acid Esters and deuterated Amino Acid Esters.