fenpropidine, a piperidine derivative,
and spiroxamine, a dioxolanemethyleneamine derivative
introduced in 1996 , belong to the same group
of fungicides.
Fenpropidin is a fungicide.
Fenpropidin is both a contact and a systemic fungicide which
provides effective eradicant control of powdery mildew, rusts and leaf
blotch in cereal.
ChEBI: A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group.
Moderately toxic by ingestion, inhalation,
and skin contact.
Limited data are available in the open literature. Information presented in
this summary is abstracted from the data evaluation published by the
Pesticide Safety Directorate (PSD, 1993). Fenpropidin is stable to aqueous
hydrolysis and photodegradation. Hydroxylation of the piperidine ring is
the primary metabolic pathway in soil and wheat plants. Hydroxylation
and oxidation of one of the methyl groups of the tert-butyl moiety are
the major reactions in rats and lactating goats. The primary metabolic
pathways of fenpropidin are presented in Scheme 1.
Fenpropidin (1)i s stable to hydrolytic degradation (50 °C)in the pH range
of 3-9 and when exposed to UV light in pH 5 buffer solution.
