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(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

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(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Basic information
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Chemical Properties
  • Boiling point:261.3±35.0 °C(Predicted)
  • Density 1.406±0.06 g/cm3(Predicted)
  • form Solid
  • pka13.30±0.20(Predicted)
  • color White
  • CAS DataBase Reference877397-65-4
Safety Information
  • HazardClass IRRITANT
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Usage And Synthesis
  • Uses(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor ( c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
  • Uses(S) -1- (2,6-dichloro-3-fluorophenyl) ethanol(C8H7C12FO) is synthesized (R)-3-[l-(2, 6-dichloro-3-fluoro-benzene)- The key intermediate of ethoxy-5- (l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -pyrimidine-2-indane. And (R)-3-[l-(2,6-dichloro-3-fluoro-benzene)-ethoxy-5-(l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -Pyrimidine-2-indane is a small molecule kinase inhibitor for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) positive for anaplastic lymphohematokinase (ALK).
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol(877397-65-4)Related Product Information
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