Ethyl 4,4,4-trifluoroacetoacetate is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.
Widely used in the synthetic process of medicine, pesticides and organic intermediate.
Intermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet
Flammability and Explosibility
Flammable
With an ethanol solution of sodium ethoxide as a catalyst and in the presence of an organic solvent, ethyl trifluoroacetate and ethyl acetate are subjected to a Claisen condensation reaction, and ethyl 4,4,4-trifluoroacetoacetate is synthesized.