Off-white to light yellow solid
3-Pyridylacetic acid serves as a starting material, together with Ln(ClO4)3·6H2O and 1,10-phenanthroline, in the preparation of lanthanide complexes [Ln2(3-PAA)2(μ-Cl)2(phen)4](ClO4)2.
ChEBI: A monocarboxylic acid that is acetic acid substituted by a (pyridin-3-yl) group. It is a metabolite of nicotine and other tobacco alkaloids.
(1) 2-(pyridin-3-yl)acetic acid hydrochloride (13.2 g, 75.6 mmol) was suspended in ethanol (100 mL) and an ethanol solution of 0.5 mol/L potassium hydroxide (150 mL) was slowly added. The reaction mixture was stirred until homogeneous and then filtered to remove the resulting potassium chloride precipitate. The filtrate was concentrated and dried to give 2-(pyridin-3-yl)acetic acid (10.6 g, quantitative yield).
[1] Patent: EP1559716, 2005, A1. Location in patent: Page/Page column 20
