Basic information Safety Related Supplier


Basic information Safety Related Supplier
MONOBROMOBIMANE Basic information
MONOBROMOBIMANE Chemical Properties
  • Melting point:152-154 °C(lit.)
  • Boiling point:327.8±44.0 °C(Predicted)
  • Density 1.66±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMF: soluble
  • form powder
  • pka-3.36±0.70(Predicted)
  • color Yellow
  • λmax398 nm
  • BRN 4430959
  • Stability:Light Sensitive
  • Biological ApplicationsGlutathione S-transferase substrates; detecting glutathione S-transferase,thiols,sulfite,homocysteine,mycothiol,sulfur compounds; thiol-reactive probes
  • CAS DataBase Reference71418-44-5
Safety Information
  • Safety Statements 22-24/25
  • WGK Germany 3
  • 8
  • Chemical PropertiesYellow Powder
  • UsesMonobromobimane readily reacts with low molecular weight thiols. Bimanes are useful for detecting the distribution of protein thiols in cells before and after chemical reduction of disulfides. Fluorescence: max. Abs. 398nm; e x 10-3: 5.0
  • UsesMonobromobimane is essentially nonfluorescent until conjugated to target molecule. It readily reacts with several low molecular weight thiols, including glutathione, mercaptopurine, peptides and plasma thiols, as well as with carboxylic acids.
  • Usesdouble labeled product that can be fixed with aldehydes for cell-lineage tracing1, neuronal tracing2 and transplantation3.
  • UsesMonobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The absorption and emission maxima for monobromobimane are 398 and 490 nm, respectively.
  • DefinitionChEBI: A pyrazolopyrazole that consists of 1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione bearing three methyl substituents at positions 2, 5 and 6 as well as a bromomethyl substituent at the 3-position.
MONOBROMOBIMANE(71418-44-5)Related Product Information
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