WSP-1

Hydrogen sulfide (H₂S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H₂S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H₂S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.¹

1. Liu, C., Pan, J., Li, S., et al. Capture and visualization of hydrogen sulfide via a fluorescent probe Angew. Chem. Int. Ed. Engl. 50(44),10327-10329(2011).