Description
Hydrogen sulfide (H
2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-
1 is a reactive disulfide-
containing, fluorescent probe designed to detect H
2S in biological samples and cells. Through a reaction-
based fluorescent turn-
on strategy, WSP-
1 selectively and rapidly reacts with H
2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.
1
References
1. Liu, C., Pan, J., Li, S., et al.
Capture and visualization of hydrogen sulfide via a fluorescent probe Angew. Chem. Int. Ed. Engl. 50(44),10327-10329(2011).
