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71418-44-5

供应商 相关产品 基本信息 理化性质 安全数据 荧光专用试剂价格(试剂级) 常见问题列表

产品图片

基本信息

中文
荧光专用试剂
英文名称
MMB
MBBR
Nsc 608544
BROMOBIMANE
THIOLYTE(R) MB
MONOBROMOBIMANE
THIOLYTE(R) MB REAGENT
MBBr [MonobroMobiMane]
THIOLYTE MONOBROMOBIMANE REAGENT
MONOBROMOBIMANE, FOR FLUORESCENCE
CAS
71418-44-5
中文名称
溴二胺
溴代双满
单溴代双满
荧光专用试剂
分子式
C10H11BrN2O2
分子量
271.11
MOL 文件
71418-44-5.mol

理化性质

熔点 
152-154 °C(lit.)

储存条件 
2-8°C

溶解度 
DMF: soluble

形态
powder
颜色
Yellow
最大波长(λmax)
398 nm
稳定性
Light Sensitive
生物领域应用
Glutathione S-transferase substrates; detecting glutathione S-transferase,thiols,sulfite,homocysteine,mycothiol,sulfur compounds; thiol-reactive probes

安全数据

安全说明 
22-24/25
WGK Germany 
3


8

荧光专用试剂价格(试剂级)

荧光专用试剂价格(试剂级)
更新日期产品编号产品名称包装价格
2021/09/07B4220溴代双满
Bromobimane
20mg1505元
2021/09/07B4220溴代双满
Bromobimane
100mg5240元

常见问题列表

生物活性
Bromobimane基本上是非荧光物质,当与小硫醇反应时,生成荧光产物。
体外研究

Bromobimanes in solution (aqueous or organic solvents of medium polarity) react with small thiols [e.g., the tripeptide thiol glutathione (GSH)], and with reactive protein thiol groups (e.g., hemoglobin). The reactions of bromobimanes with thiols are second order and dependent on pH, the active nucleophile being the thiolate anion. The reaction of bromobimane with a thiolate converts the nonfluorescent agent into water-soluble fluorescent products. The neutral agents mBBr and bBBr are moderately soluble in mediumpolarity organic solvents (acetonitrile, dichloromethane), and slightly soluble in water. The quaternary salt, qBBr, and the anionic bromobimane, SBBr, are soluble in water, but less soluble in organic solvents. Bromobimanes are yellow. The highly selective, rapid reactivity of bromobimanes toward thiols, the stability and fluorescence yield of the thiol derivatives, the ease of separation of the derivatives by reversed-phase HPLC, and the availability of both cell-penetrating and nonpenetrating forms, make the use bromobimanes an extremely powerful approach to the analysis of low molecular weight biothiols.


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