A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.
ChEBI: An aromatic ether that is aniline in which the hydrogen at position 4 is replaced by an ethoxy group. It is a hydrolysis metabolite of phenacetin.
Colorless to dark red liquid.
Very sensitive to exposure to air and light. Turns red to brown on exposure to light and air. . Slightly soluble in water.
Phenetidine reacts vigorously with powerful oxidizers.
Phenetidine is combustible.
Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. Caution: It can be absorbed through the skin. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
