Amezinium methylsulfate
- Product Name:Amezinium methylsulfate
- CAS:30578-37-1
- MF:C12H15N3O5S
- MW:313.33
- EINECS:250-248-0
- Mol File:30578-37-1.mol
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Amezinium methylsulfate Chemical Properties
- Melting point:176° (dec)
- Merck 14,394
- CAS DataBase Reference30578-37-1
- RTECS UR6066500
- ToxicityLD50 in mice, rats (mg/kg): 1630, 1410 orally; 40.4, 45.5 i.v. (Teschendorf)
- Language:EnglishProvider:6-Methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate
Amezinium methylsulfate Usage And Synthesis
- OriginatorRegulton,Nordmark,W. Germany,1981
- Manufacturing Process18.7 parts of 1-phenyl-4-aminopyridazone-(6) and 19 parts of dimethyl sulfate in 400 parts of xylene are kept at 120°C for one hour while mixing well. The reaction mixture is suction filtered, 28 parts (89.5% of the theory) of 1-phenyl-4-amino-6-methoxypyridazinium methosulfate is obtained having a melting point of 173°C to 174°C after recrystallization from acetonitrile. The perchlorate has a melting point of 179°C to 182°C.
- Therapeutic FunctionAntihypotensive
- amezinium 4-AMINOPYRIDAZINE Amezinium methylsulfate Sulfachloropyridazine sodium Hydralazine Bis(2-ethylhexyl)amine Thioridazine Doxazosin mesylate Triallylamine Dibenzylamine Pefloxacin mesylate Triethanolamine Methoxy Methanesulfonic acid Methanesulfonyl chloride Iodosulfuron-methyl 4-Methoxyphenylacetone METSULFURON METHYL
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