이마자목스 암모늄염

한글명:이마자목스 암모늄염

카스 번호114311-32-9

상품명:Imazamox

CBNumberCB6333049

분자식C15H19N3O4

포뮬러 무게305.33

MOL 파일114311-32-9.mol

동의어(한글)

이마자목스암모늄염

화학적 성질

녹는점	166-167°C
밀도	1.39 g/cm3
저장 조건	0-6°C
용해도	DMSO : 20 mg/mL (65.50 mM)
물리적 상태	Solid
산도 계수 (pKa)	pK1 2.3; pK2 3.3(at 25℃)
색상	White to off-white
InChI	InChI=1S/C15H19N3O4/c1-8(2)15(3)14(21)17-12(18-15)11-10(13(19)20)5-9(6-16-11)7-22-4/h5-6,8H,7H2,1-4H3,(H,19,20)(H,17,18,21)
InChIKey	NUPJIGQFXCQJBK-UHFFFAOYSA-N
SMILES	C1(C2NC(=O)C(C)(C(C)C)N=2)=NC=C(COC)C=C1C(O)=O
CAS 데이터베이스	114311-32-9(CAS DataBase Reference)
EPA	Imazamox (114311-32-9)

위험 및 안전 성명

위험품 표기	N
위험 카페고리 넘버	50/53
안전지침서	60-61
유엔번호(UN No.)	UN3077 9/PG 3
WGK 독일	3
유해 물질 데이터	114311-32-9(Hazardous Substances Data)
독성	LD50 (technical grade) orally in rats: >5000 mg/kg; dermally in rabbits: >4000 mg/kg; LC50 by inhalation in rats: >6.3 mg/l (Glover)

그림문자(GHS)

이마자목스 암모늄염 화학적 특성, 용도, 생산

개요
Imazamox is registered throughout the world for use in leguminous crops, including soybeans, alfalfa, and edible beans, as well as in imidazolinone-resistant crops (9). A nonionic surfactant or oil adjuvant is required for maximum activity. Imazamox is much more active when applied post-emergent to the weeds compared with pre-emergence application (9). One difference between imazamox and other imidazolinones is the much shorter interval needed before sensitive follow crops can be planted. This difference is due to the more rapid degradation of imazamox in the soil compared with other imidazolinones.
화학적 성질
Off-White Solid
용도
Imazamox is an imidazolinone based acetolactate synthase inhibitor that is utilized as a herbicide for weed control.
Pharmacology
Imazamox kills plants by inhibiting acetolactate synthase (ALS) (I50 = 1 μM), which is the first common enzyme in the biosynthesis of the branched chain amino acids, valine, leucine, and isoleucine. Imazamox is rapidly absorbed through the leaves of plants. Once it enters the plant, imazamox rapidly translocates to the growing points and growth ceases within 1 day after herbicide application, followed by chlorosis and then by necrosis of the growing points. Total plant death will occur within 2 to 3 weeks after treatment.
신진 대사
Plant Metabolism. The selectivity of imazamox is due to differential rates and routes of metabolism in tolerant crops versus susceptible weeds (10). The primary metabolic route is hydroxylation followed by conjugation to glucose. In imidazolinone-resistant crops, the primary mechanism of selectivity is due to an altered acetolactate synthase that is not inhibited by imazamox (11).
Animal Metabolism. Metabolism studies in the rat showed that imazamox is rapidly excreted in the urine. There was no accumulation of imazamox or any of its derivatives in the liver, kidney, muscle, fat, or blood (9).

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