水質分析用標準溶液 1,1,1-トリクロロエタン (1mg/mL メタノール溶液)

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H420：オゾン層を破壊し、健康及び環境に有害

• 注意書き

  P502：オゾン層への有害性

水質分析用標準溶液 1,1,1-トリクロロエタン (1mg/mL メタノール溶液) 価格

MSDS Information

• Methylchloroform

水質分析用標準溶液 1,1,1-トリクロロエタン (1mg/mL メタノール溶液) 化学特性,用途語,生産方法

• 用途

  製造用剤

• 説明

  1,1,1-Trichloroethane (1,1,1-TCE) was first identified in 1840 by Henri Victor Regnault, a French chemist and physicist. 1,1,1- TCE is a synthetic chemical that is released to the environment primarily by human industrial activity such as by-process and fugitive emissions during its manufacture, formulation, and use in both consumer and industrial products, which can then undergo thermal and photochemical chlorination. 1,1,1-TCE was originally introduced as a replacement for other chlorinated and flammable solvents like carbon tetrachloride. Although trichloroethane was formerly used extensively in a range of industrial applications and consumer products, including such products as adhesives and adhesive cleaners, lubricants, general purpose liquid cleaners and spray degreasers, oven cleaners, spot removers, shoe polish, and fabric finishes, and as a precursor for hydrofluorocarbons, it is no longer used in common household products. 1,1,1-TCE was one of the compounds addressed by the Montreal Protocol in 1987, which stipulates that the production and consumption of these potentially ozone-depleting substances in the stratosphere were to be phased out. Under this agreement, the final phase out for developed countries for 1,1,1-TCE was 1996, with selected exceptions for existing stocks and essential uses; developing countries have until 2015 for their ban to take effect.

• 化学的特性

  1,1,1-Trichloroethane is a colorless liquid. It has an odor similar to chloroform. The Odor Threshold is 120 ppm (NJ) or 400 ppm (NY).

• 物理的性質

  Colorless, watery liquid with a dusty, sooty or polish-type odor similar to chloroform. At 40 °C, the average odor threshold concentration and the lowest concentration at which an odor was detected were 20,000 and 2,200 μg/L, respectively. At 25 °C, the lowest concentration at which a taste was detected was 1,500 μg/L, respectively (Young et al., 1996). The average least detectable odor threshold concentrations in water at 60 °C and in air at 40 °C were 0.47 and 0.32 mg/L, respectively (Alexander et al., 1982).

• 使用

  1,1,1-Trichloroethane is used as a cleaningsolvent for cleaning metals and plastic molds.

• 調製方法

  Most commercial methyl chloroform, which is sold under several trade names, contains inhibitors to prevent reaction of the solvent with aluminum and alloys. This reaction produces hydrogen chloride and in confined vessels may produce high pressures.

• 定義

  ChEBI: A member of the class of chloroethanes carrying three chloro substituents at position 1.

• 一般的な説明

  A colorless liquid with a sweet, pleasant odor. May irritate skin, eyes and mucous membranes. In high concentrations the vapors may have a narcotic effect. Nonflammable, but may decompose and emit toxic chloride fumes if exposed to high temperatures. Used as a solvent.

• 空気と水の反応

  Insoluble in water. Absorbs some water.

• 反応プロフィール

  1,1,1-Trichloroethane decomposes in the presence of chemically active metals. This includes aluminum, magnesium and their alloys. 1,1,1-Trichloroethane will react violently with dinitrogen tetraoxide, oxygen, liquid oxygen, sodium and sodium-potassium alloys. 1,1,1-Trichloroethane will also react violently with acetone, zinc and nitrates. 1,1,1-Trichloroethane can react with sodium hydroxide. 1,1,1-Trichloroethane is incompatible with strong oxidizers and strong bases. Mixtures with potassium or its alloys are shock-sensitive and may explode on light impact. 1,1,1-Trichloroethane can react with an aqueous suspension of calcium hydroxide, and with chlorine in sunlight. 1,1,1-Trichloroethane will attack some forms of plastics, rubber and coatings. Upon contact with hot metal or on exposure to ultraviolet radiation, 1,1,1-Trichloroethane will decompose to form irritant gases. A cobalt/molybdenum-alumina catalyst will generate a substantial exotherm on contact with its vapor at ambient temperatures. Hazardous reactions also occur with (aluminum oxide + heavy metals). .

• 健康ハザード

  The oral and inhalation toxicity of 1,1,1-trichloroethane is of low order in animalsand humans. It is an anesthetic at highconcentrations. Exposure to its vapors at a1.5% concentration in air may be lethal tohumans. Death may result from anesthesiaand/or cardiac sensitization. Prolonged skincontact may cause defatting and reddeningof eyes. Vapors are irritant to the eyes andmucous membranes.
  The acute oral toxicity is low in testanimals. The oral LD50 values in rabbitsand guinea pigs are 5660 and 9470 mg/kg,respectively (NIOSH 1986). The carcino genicity of this compound in animals andhumans is not known.

• 火災危険

  Special Hazards of Combustion Products: Toxic and irritating gases are generated in fires.

• 接触アレルゲン

  Trichloroethane is a solvent that has wide applications in industry, such as for cold type metal cleaning and in cleaning plastic molds. It is mainly an irritant, but can also provoke allergic contact dermatitis.

• 安全性プロファイル

  Poison by intravenous route. Moderately toxic by ingestion, inhalation, skin contact, subcutaneous, and intraperitoneal routes. An experimental teratogen. Human systemic effects by ingestion and inhalation: conjunctiva irritation, hallucinations or distorted perceptions, motor activity changes, irritability, aggression, hypermotility, diarrhea, nausea or vomiting and other gastrointestinal changes. Experimental reproductive effects. Questionable carcinogen. Mutation data reported. A human skin irritant. An experimental skin and severe eye irritant. Narcotic in high concentrations. Causes a proarrhythmic activity that sensitizes the heart to epinephrine-induced arrhythmias. This sometimes will cause cardlac arrest, particularly when this material is massively inhaled as in drug abuse for euphoria.
  Under the proper conditions it can undergo hazardous reactions with aluminum oxide + heavy metals, dinitrogen tetraoxide, inhbitors, metals (e.g., magnesium, aluminum, potassium, potassium-sodium alloy), sodium hydroxide, N2O4, oxygen. When heated to decomposition it emits toxic fumes of Cl-. Used as a cleaning solvent, as a chemical intermediate to produce vinylidene chloride, and as a propellant in aerosol cans.

• 職業ばく露

  1,1,1-Trichloroethane is used as a cleaning solvent, chemical intermediate for vinylidene chloride. In liquid form it is used as a degreaser and for cold cleaning, dip-cleaning; and bucket cleaning of metals. Other industrial applications of 1,1,1-trichlroethane’s solvent properties include its use as a dry-cleaning agent; a vapor degreasing agent; and a propellant. In recent years, 1,1,1-trichloroethane has found wide use as a substitute for carbon tetrachloride.

• 発がん性

  IRIS provides a cancer descriptor of “inadequate information to assess carcinogenic potential.” This is based on inconclusive epidemiologic studies. A 2 year inhalation bioassay showed no treatment- related increase in tumors in rats and mice. The two available oral cancer bioassays in rats and mice are inadequate for evaluation of cancer potential. The compound has been shown to be rather negative in short-term tests for genotoxicity.
  NCI tested rats and mice by oral and inhalation routes, but the results were questionable. Quast et al. exposed 96 Sprague–Dawley rats of both sexes to 875 or 1750 ppm 1,1,1-trichloroethane vapor for 6 h/ day, 5 days/week for 12 months, followed by an additional 19 month observation period. The only significant sign of toxicity was an increased incidence of focal hepatocellular alterations in female rats at the highest dosage. Neither was it evident that a maximum tolerated dose was used nor was a range-finding study conducted. No significant dose-related neoplasms were reported, but these dose levels were below those used in the NCI study.
  In another study, Quast et al. used an inhibited formulation of 1,1,1-trichloroethane. Fischer 344 rats and B6C3F1 mice of both sexes were exposed to 0, 150, 500, or 1500 ppm 6 h/day, 5 days/week for 2 years. The authors indicate that there were no indications of an oncogenic effect on rats or mice following 2 years of exposure to the 1,1,1- trichloroethane formulation and a NOAEL of 500 ppm for adverse effect of any kind. The ATSDR reviewed this information (52) and determined that the study adequately demonstrated negative evidence of carcinogenicity in animals by lifetime inhalation up to 1500 ppm.

• 輸送方法

  UN2831 1,1,1-Trichloroethane, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

• 純化方法

  Wash it successively with conc HCl (or conc H2SO4), aqueous 10% K2CO3 (Na2CO3), aqueous 10% NaCl, dry it with CaCl2 or Na2SO4, and fractionally distil it. It can contain up to 3% dioxane as preservative. This is removed by washing successively with 10% aqueous HCl, 10% aqueous NaHCO3 and 10% aqueous NaCl, and distilling over CaCl2 before use. [Beilstein 1 IV 138.]

• 不和合性

  Not flammable under normal conditions. However, in close or closed spaces, it may form a dangerously explosive atmosphere. See also fireextinguishing section. Strong caustics; strong oxidizers; chemically active metals, such as aluminum, magnesium powder; sodium, potassium. Reacts slowly with water forming hydrochloric acid. Upon contact with hot metal or exposure to UV radiation, it will decompose to form hydrochloric acid, phosgene and dichloroacetylene. Forms shocksensitive mixtures with potassium or its alloys. Attacks natural rubber.

• 廃棄物の処理

  Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced. As an alternative to disposal, trichloroethane may be recovered from waste gases and liquids from various processes and recycled.

水質分析用標準溶液 1,1,1-トリクロロエタン (1mg/mL メタノール溶液) 上流と下流の製品情報

水質分析用標準溶液 1,1,1-トリクロロエタン (1mg/mL メタノール溶液) スペクトルデータ(¹³CNMR、IR1、MS、Raman)

71-55-6, 水質分析用標準溶液 1,1,1-トリクロロエタン (1mg/mL メタノール溶液) キーワード