エチドロン酸二ナトリウム

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

エチドロン酸二ナトリウム 価格

エチドロン酸二ナトリウム 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色粉末～結晶

• 用途

  酸誘導体の合成化合物骨吸収を抑制する

• 効能

  骨吸収抑制薬, 骨粗鬆症治療薬

• 商品名

  ダイドロネル (大日本住友製薬)

• 説明

  Agents in the first generation (e.g., etidronate disodium and tiludronate) that were dosed continuously produced poorly mineralized bone, because there was no interval for appropriate bone mineralization to occur. Subsequent studies that used a cyclic dosing schedule (400 mg/day for 2 weeks, followed by 2.5 months of calcium supplementation only) showed improvement in bone mineralization. Etidronate has been approved for treatment of Paget's disease of the bone but not for treatment of osteoporosis. Tiludronate is approximately 10-fold more potent than etidronate and, when given orally for 6 months (200, 400, or 800 mg/day), increases BMD by 2%. No further bone loss was detected in patients 6 months after cessation of therapy.

• 化学的特性

  White Crystalline Solid

• 使用

  Etidronate disodium is a bisphosphonate antiresorptive agent,it is used as a calcium regulator.

• 定義

  ChEBI: An organic sodium salt resulting from the replacement of two protons from etidronic acid (one from from each of the phosphonic acid groups) by sodium ions.

• 安全性プロファイル

  Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of POx, and Na2O.

エチドロン酸二ナトリウム 上流と下流の製品情報

エチドロン酸二ナトリウム 生産企業

Global(365)Suppliers

7414-83-7, エチドロン酸二ナトリウム キーワード