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Bromo-PEG5-Azide

Bromo-PEG5-Azide Structure
Bromo-PEG5-Azide
  • CAS No.1402411-90-8
  • Chemical Name:Bromo-PEG5-Azide
  • CBNumber:CB13062448
  • Molecular Formula:C12H24BrN3O5
  • Formula Weight:370.24
  • MOL File:1402411-90-8.mol
Bromo-PEG5-Azide Property
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Bromo-PEG5-Azide Chemical Properties,Usage,Production

  • Description Bromo-PEG5-azide contain a bromide group and a terminal azide. The bromide (Br) is a very good leaving group for nucleophilic reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG5 spacer increases solubility in aqueous media.
  • Uses Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG5-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG5-Azide Suppliers
Global(46)Suppliers
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Bromo-PEG5-Azide Spectrum
1402411-90-8, Bromo-PEG5-AzideRelated Search:
  • peg
  • 抑制剂
  • 基准试剂
  • 化合物 BROMO-PEG5-AZIDE
  • 1-叠氮-17-溴-3,6,9,12,15-五氧杂十七烷
  • N3-PEG5-BR
  • 溴-五聚乙二醇-叠氮
  • 溴代-六聚乙二醇-叠氮
  • 溴代-五聚乙二醇-叠氮
  • 叠氮-五聚乙二醇-溴
  • 1402411-90-8
  • 1-Azido-17-bromo-3,6,9,12,15-pentaoxaheptadecane
  • N3-PEG5-CH2CH2Br/3,6,9,12,15-Pentaoxaheptadecane, 1-azido-17-bromo-
  • N3-PEG5-CH2CH2Br
  • Azido-PEG5-Br
  • Br-PEG5-N3
  • Bromo-PEG5-Azide

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