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Bromo-PEG2-phosphonic acid ethyl ester

Bromo-PEG2-phosphonic acid ethyl ester Structure
Bromo-PEG2-phosphonic acid ethyl ester
  • CAS No.1226767-94-7
  • Chemical Name:Bromo-PEG2-phosphonic acid ethyl ester
  • CBNumber:CB33062442
  • Molecular Formula:C10H22BrO5P
  • Formula Weight:333.16
  • MOL File:1226767-94-7.mol
Bromo-PEG2-phosphonic acid ethyl ester Property
  • Boiling point 387.4±27.0 °C(Predicted)
  • Density 1.299±0.06 g/cm3(Predicted)
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Bromo-PEG2-phosphonic acid ethyl ester Chemical Properties,Usage,Production

  • Description Bromo-PEG2-phosphonic acid diethyl ester is a PEG linker containing a bromine group and a phosphonic acid diethyl ester. The bromine group is a good leaving group and participates in substitution reactions. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media.
  • Uses Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG2-phosphonic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Bromo-PEG2-phosphonic acid ethyl ester Spectrum
1226767-94-7, Bromo-PEG2-phosphonic acid ethyl esterRelated Search:
  • 2-(2-(2-溴乙氧基)乙氧基)乙基)膦酸二乙酯
  • 1226767-94-7
  • Diethyl P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]phosphonate
  • Phosphonic acid, P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, diethyl ester
  • Bromo-PEG2-phosphonic acid diethyl ester
  • Bromo-PEG2-phosphonic acid ethyl ester

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