ChemicalBook > CAS DataBase List > Br-PEG6-bromide
Br-PEG6-bromide
Br-PEG6-bromide
- CAS No.72713-23-6
- Chemical Name:Br-PEG6-bromide
- CBNumber:CB73303330
- Molecular Formula:C14H28Br2O6
- Formula Weight:452.18
- MOL File:72713-23-6.mol
Br-PEG6-bromide Property
- Boiling point 451.0±40.0 °C(Predicted)
- Density 1.394±0.06 g/cm3(Predicted)
- form Liquid
- color Light yellow to yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Br-PEG6-bromide Chemical Properties,Usage,Production
- Description Bromo-PEG6-bromide is a PEG linker containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
- Uses Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
- IC 50 PEGs
-
References
[1] Mulyana Y, et al. Oligonuclear polypyridylruthenium(II) complexes incorporating flexible polar and non-polar bridges: synthesis, DNA-binding and cytotoxicity. Dalton Trans. 2011 Feb 21;40(7):1510-23. DOI:10.1039/c0dt01250e
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Br-PEG6-bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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72713-23-6, Br-PEG6-bromideRelated Search:
- 抑制剂
- PEG系列产品-Br-PEG系列
- C14H28Br2O6
- 化合物 BROMO-PEG6-BROMIDE
- 1,20-二溴-3,6,9,12,15,18-六氧代二十烷
- 溴-PEG6-溴
- 双溴代六聚乙二醇
- 溴-六聚乙二醇-溴
- 溴代-六乙二醇-溴代
- 72713-23-6
- 3,6,9,12,15,18-Hexaoxaeicosane, 1,20-dibromo-
- Br-PEG6-CH2CH2Br/3,6,9,12,15,18-Hexaoxaeicosane, 1,20-dibromo-
- 1,2-Bis-{2-[2-(2-bromo-ethoxy)-ethoxy]-ethoxy}-ethane
- Br-PEG6-Br
- Br-PEG6-CH2CH2Br
- Br-PEG6-bromide