Br-PEG3-CH2CO2H
Br-PEG3-CH2CO2H
- CAS No.1346502-15-5
- Chemical Name:Br-PEG3-CH2CO2H
- CBNumber:CB63303328
- Molecular Formula:C8H15BrO5
- Formula Weight:271.11
- MOL File:1346502-15-5.mol
Br-PEG3-CH2CO2H Property
- Boiling point 379.7±27.0 °C(Predicted)
- Density 1.446±0.06 g/cm3(Predicted)
- pka 3.39±0.10(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Br-PEG3-CH2CO2H Chemical Properties,Usage,Production
- Description Bromo-PEG3-CH2CO2H is a PEG linker containing a bromide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.
- Uses Br-PEG3-CH2COOH (compound 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
- IC 50 PEGs
- References [1] Zha Z, et al. Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA). J Med Chem. 2011 Dec 8;54(23):8085-98. DOI:10.1021/jm2009106
Br-PEG3-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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1346502-15-5, Br-PEG3-CH2CO2HRelated Search:
- Bromo-PEG3-t-butyl ester Bromo-PEG1-Acid 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- Bromo-PEG1-t-butyl ester 1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE Bromo-PEG4-acid Bromo-PEG2-acid Bromo-PEG2-t-butyl ester 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE Acetic acid, 2-[2-(2-bromoethoxy)ethoxy]- BocNH-PEG5-CH2CH2Br
- C8H15BrO5
- 2-(2-(2-(2-溴乙氧基)乙氧基)乙氧基)乙酸
- 溴-三聚乙二醇-亚甲基羧酸
- BR-PEG3-乙酸
- 溴代-三聚乙二醇-乙酸
- 1346502-15-5
- Br-PEG3-CH2COOH/Acetic acid, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
- 2-(2-(2-(2-Bromoethoxy)ethoxy)ethoxy)acetic acid
- Acetic acid, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
- Br-PEG3-CH2COOH
- Bromo-PEG3-CH2COOH
- Bromo-PEG3-CH2CO2H
- Br-PEG3-CH2CO2H