ChemicalBook > CAS DataBase List > Bromo-PEG1-Acid
Bromo-PEG1-Acid
Bromo-PEG1-Acid
- CAS No.1393330-33-0
- Chemical Name:Bromo-PEG1-Acid
- CBNumber:CB73062435
- Molecular Formula:C5H9BrO3
- Formula Weight:197.03
- MOL File:1393330-33-0.mol
Bromo-PEG1-Acid Property
- storage temp. -20°C
- solubility DMSO : 100 mg/mL (507.54 mM; Need ultrasonic)
- form Liquid
- color Colorless to light yellow
- UNSPSC Code 12352101
Safety
- HS Code :2918999090
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P261-P305+P351+P338
Bromo-PEG1-Acid Price
More Price(1)
- Brand: Sigma-Aldrich(India)
- Product number: 901573
- Product name : Bromo-PEG1-acid
- Purity: ≥95%
- Packaging: 50MG
- Price: ₹16432.35
- Updated: 2022/06/14
- Buy: Buy
Bromo-PEG1-Acid Chemical Properties,Usage,Production
- Description Bromo-PEG1-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
- Uses Bromo-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
- reaction suitability reagent type: linker
Bromo-PEG1-Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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1393330-33-0, Bromo-PEG1-AcidRelated Search:
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