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Bromo-PEG6-t-butyl ester

Bromo-PEG6-t-butyl ester Structure
Bromo-PEG6-t-butyl ester
  • CAS No.1393330-41-0
  • Chemical Name:Bromo-PEG6-t-butyl ester
  • CBNumber:CB13062453
  • Molecular Formula:C19H37BrO8
  • Formula Weight:473.4
  • MOL File:1393330-41-0.mol
Bromo-PEG6-t-butyl ester Property
  • Boiling point 489.9±40.0 °C(Predicted)
  • Density 1.192±0.06 g/cm3(Predicted)
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Bromo-PEG6-t-butyl ester Chemical Properties,Usage,Production

  • Description Bromo-PEG6-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
  • Uses Bromo-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs; Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG6-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Bromo-PEG6-t-butyl ester Spectrum
1393330-41-0, Bromo-PEG6-t-butyl esterRelated Search:
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  • Bromo-PEG6-Boc
  • CAS_1393330-41-0
  • Br-PEG6-CH2CH2COOtBu
  • 4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-bromo-, 1,1-dimethylethyl ester
  • Br-PEG6-COOtBu
  • Br-PEG6-t-butyl ester
  • Bromo-PEG7-t-butyl ester
  • Bromo-PEG6-t-butyl ester

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