ChemicalBook > CAS DataBase List > Bromo-PEG8-t-butyl ester
Bromo-PEG8-t-butyl ester
Bromo-PEG8-t-butyl ester
- CAS No.1623792-00-6
- Chemical Name:Bromo-PEG8-t-butyl ester
- CBNumber:CB43062454
- Molecular Formula:C23H45BrO10
- Formula Weight:561.5
- MOL File:1623792-00-6.mol
Bromo-PEG8-t-butyl ester Property
- Boiling point 557.0±45.0 °C(Predicted)
- Density 1.180±0.06 g/cm3(Predicted)
- form Liquid
- color Colorless to light yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Bromo-PEG8-t-butyl ester Chemical Properties,Usage,Production
- Description Bromo-PEG8-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
- Uses Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- IC 50 PEGs; Alkyl/ether
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG8-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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1623792-00-6, Bromo-PEG8-t-butyl esterRelated Search:
- Bromo-PEG2-azide Bromo-PEG2-t-butyl ester Bromo-PEG6-alcohol Ethanol, 2-[2-(2-bromoethoxy)ethoxy]- Bromo-PEG2-acid Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]- Ethanol, 2-(2-bromoethoxy)- Bromo-PEG3-t-butyl ester 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- Bromo-PEG3-Acid Bromo-PEG5-t-butyl ester Bromo-PEG5-PFP ester Bromo-PEG6-t-butyl ester
- 有机试剂
- 抑制剂
- PEG系列产品-Br-PEG系列
- 助剂
- C23H45BrO10
- 化合物 BROMO-PEG8-BOC
- 溴-八聚乙二醇-叔丁酯
- 1-溴-3,6,9,12,15,18,21,24-八氧杂二十七烷-27-酸叔丁酯
- 溴-PEG8-丙酸叔丁酯
- 溴-八聚乙二醇-丙酸叔丁酯
- 溴代-七聚乙二醇-丙酸叔丁酯
- 溴代-九聚乙二醇-丙酸叔丁酯
- 溴代-八聚乙二醇-丙酸叔丁酯
- 溴代-八乙二醇-丙酸叔丁酯
- 1623792-00-6
- tert-Butyl 1-bromo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
- Br-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-bromo-, 1,1-dimethylethyl ester
- Bromo-PEG8-Boc
- CAS_1623792-00-6
- Br-PEG8-CH2CH2COOtBu
- Br-PEG8-COOtBu
- 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-bromo-, 1,1-dimethylethyl ester
- tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- Br-PEG8-t-butyl ester
- Bromo-PEG9-t-butyl ester
- Bromo-PEG8-t-butyl ester