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ERYTHROSIN B

CAS No.16423-68-0
Chemical Name:ERYTHROSIN B
CBNumber:CB0393696
Molecular Formula:C20H9I4NaO5
Formula Weight:859.89
MOL File:16423-68-0.mol

ERYTHROSIN B Property

Melting point 142~144℃
Density 0.98
bulk density 470kg/m3
vapor pressure 0Pa at 25℃
Flash point 285℃
storage temp. room temp
solubility 100g/l
form Fine Powder
Colour Index 45430
pka 4.1(at 25℃)
color Deep red to brown
PH Range 0(yellow)-3.6(red)
PH 6-7 (10g/l, H2O, 20℃)
Water Solubility Soluble in water
ε(extinction coefficient) ≥13000 at 308-312nm
≥32000 at 259-263nm
λmax 525nm
Merck 14,3693
BRN 1443945
Stability Stable. Incompatible with strong oxidizing agents.
Biological Applications Detecting gene expression,phosphoproteins,protease,stress biomarkers; treating age-related macular degeneration,arteriosclerosis,bone metabolic diseases,burns,cancer,diabetes,human immunodeficiency virus infection,obesity
Major Application color filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy
InChIKey RAGZEDHHTPQLAI-UHFFFAOYSA-L
LogP -1.163 at 25℃
FDA 21 CFR 74.1303; 74.303
Substances Added to Food (formerly EAFUS) FD&C RED NO. 3
CAS DataBase Reference 16423-68-0
FDA UNII 8TL7LH93FM
EPA Substance Registry System Erythrosine B (16423-68-0)
UNSPSC Code 85151701
NACRES NA.47

Safety

Hazard Codes :Xn
Risk Statements :22
Safety Statements :36
WGK Germany :3
RTECS :LM5950000
HS Code :32129000
Hazardous Substances Data :16423-68-0(Hazardous Substances Data)
Toxicity :LD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell)

NFPA 704:

	1
2		1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H411
Precautionary statements P264-P270-P273-P301+P312-P391-P501

ERYTHROSIN B Price More Price(10)

Brand: Sigma-Aldrich(India)
Product number: E8886
Product name : Erythrosin extra bluish
Purity: certified by the Biological Stain Commission
Packaging: 25G
Price: ₹4284.6
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 45690
Product name : Erythrosin extra bluish
Purity: for microscopy (Bact., Hist.), adsorption and fluorescent indicator
Packaging: 10G
Price: ₹2952.6
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 87613
Product name : Erythrosin B
Purity: analytical standard
Packaging: 25MG
Price: ₹13453.2
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 45690
Product name : Erythrosin extra bluish
Purity: for microscopy (Bact., Hist.), adsorption and fluorescent indicator
Packaging: 50G
Price: ₹9301.8
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 198269
Product name : Erythrosin B
Purity: certified by the Biological Stain Commission, Dye content ≥85?%
Packaging: 25G
Price: ₹7259.4
Updated: 2022/06/14
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ERYTHROSIN B Chemical Properties,Usage,Production

Description FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.
The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.
FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .
Chemical Properties red to brown powder
Uses Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.
Uses antibacterial
Uses Biological stain; color additive.
Uses Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.
Preparation fluorescent element (C.I. Acid Yellow 73, C.I. 45350) or ethanol in aqueous solution of the four iodine, then into sodium salt.
Definition ChEBI: An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.
General Description Erythrosin B (C.I. 45430)for microscopy Certistain^?, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain^? dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
Flammability and Explosibility Not classified
Biochem/physiol Actions Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. Erythrosin B is an artificial food dye that induces hyperkinesis when swallowed by susceptible children. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.
storage Room temperature

Properties and Applications blue light pink. Soluble in water is cherry red, no fluorescence. The strong sulfuric acid is palm in light yellow, diluted into palm yellow light precipitation. In water solution to join sodium hydroxide to create soluble red precipitate.

Standard	Light Fastness	Soaping		Persperation Fastness	Oxygen bleaching		Fastness to seawater
Standard	Light Fastness	Fading	Stain	Persperation Fastness	Fading	Stain	Fading	Stain
ISO	1	3		4	1		2-3