ChemicalBook > CAS DataBase List > 4-Iodoanisole

4-Iodoanisole

Description References

4-Iodoanisole

CAS No.696-62-8
Chemical Name:4-Iodoanisole
CBNumber:CB6450614
Molecular Formula:C7H7IO
Formula Weight:234.03
MOL File:696-62-8.mol

4-Iodoanisole Property

Melting point 50-53 °C(lit.)
Boiling point 237 °C726 mm Hg(lit.)
Density 1.7904 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in ethanol, ether, chloroform.
form Crystalline Powder and Chunks
color Off-white to brown
Sensitive Light Sensitive
BRN 1906692
InChIKey SYSZENVIJHPFNL-UHFFFAOYSA-N
CAS DataBase Reference 696-62-8(CAS DataBase Reference)
NIST Chemistry Reference Benzene, 1-iodo-4-methoxy-(696-62-8)
EPA Substance Registry System Benzene, 1-iodo-4-methoxy- (696-62-8)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xi,Xn
Risk Statements :36/37/38
Safety Statements :26-36-24/25
WGK Germany :3
F :8
TSCA :Yes
HS Code :29093090

NFPA 704:

	0
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

4-Iodoanisole Price More Price(4)

Brand: Sigma-Aldrich(India)
Product number: I7608
Product name : 4-Iodoanisole
Purity: 98%
Packaging: 25G
Price: ₹3080
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: I7608
Product name : 4-Iodoanisole
Purity: 98%
Packaging: 100G
Price: ₹11409.55
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: I0378
Product name : 4-Iodoanisole
Purity: min. 99.0 %
Packaging: 25G
Price: ₹2700
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: I0378
Product name : 4-Iodoanisole
Purity: min. 99.0 %
Packaging: 100G
Price: ₹7700
Updated: 2022/05/26
Buy: Buy

4-Iodoanisole Chemical Properties,Usage,Production

Description 4-Iodoanisole (chemical formula: C7H7IO) is an organic compound being soluble in ethanol, ether and chloroform. It has a wide range of medicals industrial applications. For example, it can be used as human and animal nutrition products, antiseptics, disinfectants, pharmaceutical intermediates, polarizing films for liquid crystal display (LCD) chemicals. Its iodine derivatives can also be used as organic building blocks and analytic reagents.
References https://www.fishersci.pt/shop/products/4-iodoanisole-98-7/11480113
Chemical Properties off-white to brown crystalline powder and chunks. Melting point 51-52 ℃, boiling point 237 ℃ (96.8kPa). Soluble in organic solvents such as alcohol and ether, but insoluble in water. Iodine can be easily separated and analyzed by light.
Uses 4-Iodoanisole is used in wide range of medicals industrial applications as well as in human and animal nutrition products, pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals. Iodine derivatives are also used as organic building blocks, analytical reagents.
Preparation 4-Iodoanisole is synthesized by the reaction of anisole with iodine chloride. Add anisole to glacial acetic acid, stir and slowly add iodine chloride. After the addition was completed, the temperature was refluxed for 3.5h. Cool, pour into ice water, and precipitate p-iodoanisole. After it was separated, the free iodine was washed with 5% sodium sulfite, then washed with water, distilled under reduced pressure, and the fractions with a boiling point of 140-160 °C (5.33 kPa) were collected and cooled to 0 °C for filtration. Wash with methanol and recrystallize to obtain the finished product.
Definition ChEBI: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein) is a member of methoxybenzenes.
Synthesis Reference(s) The Journal of Organic Chemistry, 58, p. 2058, 1993 DOI: 10.1021/jo00060a020
Tetrahedron Letters, 27, p. 3497, 1986 DOI: 10.1016/S0040-4039(00)84832-7
Purification Methods Crystallise 4-iodoanisole from aqueous EtOH and/or distil it under vacuum. [Beilstein 6 H 208, 6 I 109, 6 II 199, 6 III 744, 6 IV 1075.]